Current Treatment Approaches for The Management of Guillain Barre Syndrome: A Narrative Review of Physiotherapy Approaches: Current Treatment Approaches for The Management of Guillain Barre Syndrome

Mira Amer; Xhennet Muriqi; Mouna Khosravi; Meltem Şenel; Rustem Mustafaoglu

doi:10.5281/zenodo.10893145

Authors

Mira Amer Bethlehem University, Faculty of Nursing and Health Science, Department of Physical and Occupational Therapy https://orcid.org/0000-0001-5107-7348
Xhennet Muriqi Istanbul University-Cerrahpaşa, Institute of Graduate Studies, Department of Physiotherapy and Rehabilitation https://orcid.org/0000-0002-6302-745X
Mouna Khosravi Istanbul University-Cerrahpaşa, Institute of Graduate Studies, Department of Physiotherapy and Rehabilitation https://orcid.org/0009-0009-6213-6097
Meltem Şenel Istanbul University-Cerrahpaşa, Institute of Graduate Studies, Department of Physiotherapy and Rehabilitation https://orcid.org/0000-0001-8713-536X
Rustem Mustafaoglu Istanbul University-Cerrahpasa, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation https://orcid.org/0000-0001-7030-0787

DOI:

https://doi.org/10.5281/zenodo.10893145

Keywords:

Guillain-Barre Syndrome, Physiotherapy, Multidisciplinary Rehabilitation

Abstract

In this review we explore the current physiotherapy treatment approaches for Guillain-Barre Syndrome (GBS), an immune-mediated peripheral nervous system disorder. Examining GBS epidemiology reveals its rarity, diverse clinical variants, and increased incidence with age. The pathogenesis involves subtypes like acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and axonal variants, with infections, particularly C. jejuni, playing a role. The diagnostic methods include nerve conduction velocity tests and cerebrospinal fluid examination. GBS is characterized by progressive complications, ranging from muscular weakness to cardiovascular issues. The crucial role of physiotherapy in GBS assessment and treatment is emphasized, covering various evaluations and rehabilitation strategies. Multidisciplinary rehabilitation, exercise training, pulmonary rehabilitation, electrical stimulation, robotic rehabilitation, virtual reality, and alternative therapies are discussed. This article stresses the need for high-quality trials, especially in the context of the observed connection between COVID-19 and GBS. It underscores the importance of physiotherapy in GBS treatment, prompting further research and consideration of alternative methods like telerehabilitation.

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Current Treatment Approaches for The Management of Guillain Barre Syndrome: A Narrative Review of Physiotherapy Approaches